Seminar Notice Statistical Laboratory Iowa State University DATE AND TIME: Thursday, November 6, 1997, 1:10 p.m. PLACE: 171 Durham SPEAKER: Marek Brabec Department of Statistics Iowa State University TITLE: Simple Adjustment Procedure for Asymptotic Bias Removal and Its Applications ABSTRACT We develop a two-step estimation technique termed Adjusted Quasi Maximum Likelihood Estimation, (AQMLE). It starts with a quasi maximum likelihood estimate (QMLE), obtained by maximization of an incorrect likelihood (quasilikelihood). The quasilikelihood is often a simplified approximation to the correct likelihood, used to avoid excessive numerical computations required to maximize the true likelihood. On the second step, the QMLE is adjusted to remove asymptotic bias. The adjustment is defined implicitly through the expectation of the quasiscore under the correct model. When the QMLE is easy to obtain, the AQMLE has an advantage of rather stable computational requirements even for large n. Hence it provides a practical alternative to the MLE, when evaluation of the correct likelihood is complicated or when complete data are not accessible. The AQMLE is consistent and asymptotically normal, allowing for construction of approximate tests and confinfidence intervals. Finite sample behavior is explored in a censored lognormal-normal convolution model, describing a practical situation encountered when the concentration of a chemical substance in a particular material is measured with error and data are censored as the result of a detection limit. In a simulation study, the AQMLE is compared with the rarely used MLE (requiring separate numerical integration for each observation) and a commonly used but asymptotically biased QMLE.